Neurobiological and Physiological Decay Induced by Persistent MDMA Abuse: Clinical Evidence and Symptomatic Profiles in a Decade-Long Case Study

Authors

  • Chawki Bougoffa Mohamed Lamine Debaghine University , Setif2 (Algeria)
  • Hamid Oumelili Mohamed Lamine Debaghine University , Setif2 (Algeria)

Keywords:

Narcotics, MDMA (Ecstasy), Mental Health, Substance Dependency

Abstract

Narcotics fundamentally compromise individual psychological and mental integrity, fostering maladaptive societies characterized by systemic substance dependency. Given that public health is the cornerstone of a stable society, this research examines the deleterious effects of MDMA (Ecstasy) on the central nervous system and its long-term disruption of vital neurobiological and cognitive functions. This study aims to identify the specific psychological and physiological repercussions of MDMA abuse. Employing a descriptive-analytical approach and a clinical case study methodology, the research analyzes the profile of a young male with a decade-long history of addiction. The findings characterize Ecstasy as a lethal hallucinogenic agent that severely impairs sensorimotor functions and neurological pathways. Results indicate that chronic dependency leads to critical medical outcomes, including cerebrovascular accidents (strokes) resulting from neural cellular damage, as well as renal insufficiency, arterial spasms, and reproductive dysfunction.

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Published

2026-05-21

Issue

Section

Articles